Search Results - campus+%3e+stony+brook+university

249 Results

Sort By:

Artificial Polymeric Valves System and Methods of Making and Using Thereof

Polymeric Valve Systems for Transcatheter Aortic Valve Replacement Background: Heart valve related diseases remain a significant public health issue affecting an estimated 2% of the population with 4% of those over 65 having aortic stenosis (AS), a narrowing of the valve opening which can lead to heart failure. The traditional treatment for AS,...

Published: 4/23/2025 | Inventor(s): Brandon Kovarovic, Danny Bluestein, Ryan Helbock

Keywords(s):

Category(s): Technology Classifications > Material and Composites, Technology Classifications > Medical Devices, Campus > Stony Brook University

SeeMe: A novel tool for measuring and detecting human consciousness

An objective and quantifiable tool that can be used to measure the level of human consciousness in comatose patients Background: Assessing the functional state of the brain and predicting recovery of consciousness following acute brain injury (ABI) remains a major unsolved clinical problem. Currently, behavioral measures of recovery with scoring...

Published: 4/23/2025 | Inventor(s): Sima Mofakham, Charles Mikell, Xi Cheng

Keywords(s):

Category(s): Campus, Technology Classifications > Computer Software, Technology Classifications > Diagnostics, Technology Classifications > Medical Devices, Campus > Stony Brook University

A Point-of-care Ultrasonography Simulation System for Educational Use in Non-Stationary Medical Environments

A Point-of-care Ultrasonography Simulation System for Educational Use in Non-Stationary Medical Environments Background: Given recent advances in size, durability, and cost, the use of portable ultrasound systems has expanded within the prehospital environment. Point-of-care ultrasonography (POCUS) describes focused diagnostic ultrasound exams performed...

Published: 4/23/2025 | Inventor(s): Lauren Maloney, Griffin Walker, Thea Vijaya Kumar, Alexander Mertz, Daniella Hébert, Taelyn Kupec, Sean Reagan, Alexander Eichert

Keywords(s):

Category(s): Technology Classifications > Computer, Technology Classifications > Computer Software, Technology Classifications > Education and Training, Technology Classifications > Medical Devices, Technology Classifications > Medical Imaging, Technology Classifications > Sensors, Technology Classifications > Wireless Technology, Campus > Stony Brook University

Sts-/- mice

An animal model to study the pathogenesis of infectious diseases and test potential therapeutic solutions Background: Phosphatases Sts-1 and Sts-2 are two homologous proteins in humans which act as negative regulators of T cell receptor (TCR) signaling. These proteins regulate immune signaling through activity catalyzed by their shared C-terminal...

Published: 4/15/2025 | Inventor(s): Nick Carpino

Keywords(s):

Category(s): Campus > Stony Brook University

A Closed-Loop Stimulation Controller for Exploring Neural States

A brand-new type of reinforcement learning algorithm RSS.HDBackground> Background: < Current day algorithms governing how medical devices deliver stimulation to patients have not changed in well over 50 years and cannot account for neurological variabilities across individuals that come about from differences in genetics, lifestyle factors,...

Published: 4/2/2025 | Inventor(s): Ian Jordan, Il Park, Josue Nassar

Keywords(s):

Category(s): Technology Classifications > Artificial Intelligence, Technology Classifications > Computer Software, Technology Classifications > Therapeutics, Technology Classifications > Medical Devices, Campus, Campus > Stony Brook University

LpxC Inhibitors for Gram-Negative Infections

Treatment of multidrug-resistant bacterial infections with LpxC inhibitors for reduced drug resistance and improved safety profiles RSS.HDBackground> Background: < Infection by Gram‑negative bacteria such as Pseudomonas aeruginosa, β‑lactamase producing (ESBL) Enterobacteriaceae, and Acinetobacter baumannii is a major health problem, especially...

Published: 3/19/2025 | Inventor(s): Peter Tonge, Fereidoon Daryaee, Sneha Basak

Keywords(s):

Category(s): Technology Classifications > Drug Design and/or Synthesis, Technology Classifications > Therapeutics, Campus > Stony Brook University

Design and Synthesis of Novel Methotrexate Conjugated MicroRNA Mimic Modified with 5-Fluorouracil and/or Gemcitabine as a Platform Technology for Cancer Treatment

A platform for modifying miRNAs and using the modified miRNAs as novel cancer therapeutics. RSS.HDBackground> Background: < Resistance to chemotherapy can be a highly complex issue, with epigenetic alterations playing a key role in tumorigenesis and chemotherapy resistance. The failure to treat several advanced solid tumors can be often attributed...

Published: 3/19/2025 | Inventor(s): Jingfang Ju, Iwao Ojima, John Yuen, Lei Chen

Keywords(s):

Category(s): Technology Classifications > Therapeutics, Technology Classifications > Drug Design and/or Synthesis, Campus > Stony Brook University

Handheld Terahertz Three-dimensional Spectral Scanner

A portable handheld spectral reflection (PHASR) scanner to characterize, diagnose burn injuries and predict wound healing outcomes Background: Terahertz time-domain spectroscopy is a technique that has shown promise in biomedical imaging for the diagnosis of burn wounds. However, current portable terahertz imagers are either limited by size, requiring...

Published: 4/15/2025 | Inventor(s): Mohammad Arbab, Zachery Harris

Keywords(s):

Category(s): Technology Classifications > Diagnostics, Technology Classifications > Medical Imaging, Technology Classifications > Optics and Photonics, Campus > Stony Brook University

Concerted, Selective Radiometallation and Photo-triggered Release of Ready-to-Inject Radiopharmaceuticals from the Solid Phase

Solid Phase Radiometallation Photorelease method for the preparation of injectable radiopharmaceuticals RSS.HDBackground> Background: < Radiopharmaceuticals are agents which enable non-invasive patient diagnosis and personalized therapeutic intervention strategies. Radionuclides used in nuclear medicine applications must be purified after nuclear...

Published: 2/4/2025 | Inventor(s): Eszter Boros, Dariusz Śmiłowicz

Keywords(s):

Category(s): Technology Classifications > Diagnostics, Technology Classifications > Drug Design and/or Synthesis, Campus > Stony Brook University

An anti-capsular antibody that cross protects against clade 1 Carbapenem-resistant Klebsiella pneumoniae

A monoclonal antibody that exhibits cross-protective efficacy against multiple ST258 CR-Kp strains RSS.HDBackground> Background: < Therapeutic monoclonal antibodies (mAbs) have emerged as a dominant therapeutic modality to treat cancer, immune disorders, and infectious diseases such as high-mortality Carbapenem-resistant Klebsiella pneumoniae...

Published: 2/4/2025 | Inventor(s): Kasturi Banerjee, Bettina Fries, Michael Motley

Keywords(s):

Category(s): Technology Classifications > Therapeutics, Technology Classifications > Antibodies, Campus > Stony Brook University

1 2 3 4 5 6 7 8 9 10 ...