Search Results - peter+tonge

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LpxC Inhibitors for Gram-Negative Infections

Treatment of multidrug-resistant bacterial infections with LpxC inhibitors for reduced drug resistance and improved safety profiles RSS.HDBackground> Background: < Infection by Gram‑negative bacteria such as Pseudomonas aeruginosa, β‑lactamase producing (ESBL) Enterobacteriaceae, and Acinetobacter baumannii is a major health problem, especially...

Published: 3/7/2025 | Inventor(s): Peter Tonge, Fereidoon Daryaee, Sneha Basak

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Category(s): Technology Classifications > Drug Design and/or Synthesis, Technology Classifications > Therapeutics, Campus > Stony Brook University

Positron Emission Tomography (PET) Radiotracer

Composition, method and diagnostic use of positron imaging tomography imaging agent for bacterial infection detectionRSS.HDBackground> Background: <Positron emission tomography (PET) radiotracer is a diagnostic tool to detect bacterial infection in humans. A deficiency exists in clinical diagnostic tools capable of identifying bacterial infections...

Published: 2/1/2024 | Inventor(s): Peter Tonge, Yong Li, Fereidoon Daryaee, Peter Smith-Jones, Labros Meimetis

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Category(s): Technology Classifications > Diagnostics, Technology Classifications > Medical Imaging, Technology Classifications > Research Tools and Reagents, Campus, Campus > Stony Brook University

A Novel PET Imaging Agent for Diagnosing Bacterial Infections

A PET tracer, [18F]F-PABA which is taken up only by bacterial cells thus making it specific for diagnosing infection. Background: Bacterial infections such as those of prosthetic joints, bones (osteomyelitis) and heart valves (infective endocarditis) are difficult to diagnose and treat, and are a major cause of mortality, morbidity and health care...

Published: 9/9/2024 | Inventor(s): Peter Tonge, Zhuo Zhang, Peter Smith-Jones, Hui Wang, Li Liu

Keywords(s): Technologies

Category(s): Campus > Stony Brook University, Technology Classifications > Diagnostics, Technology Classifications > Research Tools and Reagents