Search Results - eszter+boros

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Concerted, Selective Radiometallation and Photo-triggered Release of Ready-to-Inject Radiopharmaceuticals from the Solid Phase

Solid Phase Radiometallation Photorelease method for the preparation of injectable radiopharmaceuticals RSS.HDBackground> Background: < Radiopharmaceuticals are agents which enable non-invasive patient diagnosis and personalized therapeutic intervention strategies. Radionuclides used in nuclear medicine applications must be purified after nuclear...

Published: 2/4/2025 | Inventor(s): Eszter Boros, Dariusz Śmiłowicz

Keywords(s):

Category(s): Technology Classifications > Diagnostics, Technology Classifications > Drug Design and/or Synthesis, Campus > Stony Brook University

Metal-mediated, Autolytic Amide Bond Cleavage for the Selective, Metal-Complexation Catalyzed, Controlled Release of Metallodrugs

Autolytic, metal complex-mediated amide bond cleavage for prodrug activation and synthesis of metallodrugs RSS.HDBackground> Background: < Clinically viable prodrugs release activated drug molecules at the site of interest, requiring close spatiotemporal control. Bond cleavage strategies for the release of the activated drug often incorporate...

Published: 2/4/2025 | Inventor(s): Eszter Boros, Dariusz Śmiłowicz

Keywords(s):

Category(s): Technology Classifications > Drug Design and/or Synthesis, Technology Classifications > Drug Delivery, Campus, Campus > Stony Brook University

Immunostimulant-Cytotoxic Conjugates for Targeted Cancer Therapy

050-9150 Immunostimulant-Cytotoxic Conjugates for Targeted Cancer Therapy A unique immunotherapy paradigm to treat castrate-resistant prostate cancer and its metastatic form RSS.HDBackground> Background: < Prostate cancer is one of the leading causes of cancer death, with 1 in 10 men diagnosed in their lifetime and 1 in 41 dying from the...

Published: 9/25/2024 | Inventor(s): Labros Meimetis, Eszter Boros

Keywords(s): Technologies

Category(s): Technology Classifications > Drug Design and/or Synthesis, Technology Classifications > Drug Delivery, Technology Classifications > Therapeutics, Campus > Stony Brook University

Triazamacrocycle-derived Chelators for the Coordination of Imaging and Therapy Metal Ions

Rapid and inert radiolabeling with an array of radioactive isotopes suitable for medical imaging and therapy approaches. Background: Personalized medicine, or individually tailored patient treatment, is an emerging clinical management paradigm. In nuclear medicine, this entails exploiting diagnostic techniques, such as non-invasive imaging by means...

Published: 2/28/2024 | Inventor(s): Eszter Boros, Brett Vaughn

Keywords(s): Technologies

Category(s): Campus > Stony Brook University, Technology Classifications > Medical Imaging