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Modular Control of a Bioorthogonal Ligation

Caged cyclopropenes that are unreactive until activated for controlling bioorthogonal reactivity Background: Significant effort has been devoted to optimizing and discovering bioorthogonal reagents that are faster, fluorogenic, and orthogonal to the already existing bioorthogonal repertoire. Conversely, efforts to explore bioorthogonal reagents whose...

Published: 2/28/2024 | Inventor(s): Scott Laughlin, Pratik Kumar, Ting Jiang

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Category(s): Campus > Stony Brook University, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays, Technology Classifications > Therapeutics

Landscape Emulation and Locomotion Development through Virtual Reality

A system for generating a progressive representation associated with surjectively mapped virtual and physical reality image data. Background: Virtual reality (VR) creates an illusion for the user; typically it puts them in an artificially created world. VR may be achieved through stimulating senses that already occur in the user, such as sight and...

Published: 11/22/2023 | Inventor(s): Arie Kaufman, Qi Sun, Li-Yi Wei

Keywords(s): Technologies

Category(s): Campus > Stony Brook University, Technology Classifications > Computer, Technology Classifications > Computer Software, Technology Classifications > Information Technology, Technology Classifications > Screens and Assays

High-Throughput 3-D Invasion Assay

A novel invasion plate design and methods which enables increased throughput, standardization and quantification of cell invasion. Background: The ability of cancer cells to invade into surrounding matrices is a critical determinant of metastasis and failure to prevent metastasis has reinforced the unmet need of targeting cancer invasion. To expedite...

Published: 3/16/2023 | Inventor(s): Jian Cao, Yizhi Meng, Vincent Alford

Keywords(s): Technologies

Category(s): Campus > Stony Brook University, Technology Classifications > Screens and Assays, Technology Classifications > Therapeutics, Technology Classifications > Research Tools and Reagents