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Immunostimulant-Cytotoxic Conjugates for Targeted Cancer Therapy

050-9150 Immunostimulant-Cytotoxic Conjugates for Targeted Cancer Therapy A unique immunotherapy paradigm to treat castrate-resistant prostate cancer and its metastatic form RSS.HDBackground> Background: < Prostate cancer is one of the leading causes of cancer death, with 1 in 10 men diagnosed in their lifetime and 1 in 41 dying from the...

Published: 3/16/2023 | Inventor(s): Labros Meimetis, Eszter Boros

Keywords(s): Technologies

Category(s): Technology Classifications > Drug Design and/or Synthesis, Technology Classifications > Drug Delivery, Technology Classifications > Therapeutics, Campus > Stony Brook University

Bioresorbable Zinc-Based Surgical Staples

050- 9154 InPart Bioresorbable Zinc-Based Surgical Staples Biodegradable and implantable implants made of metallic zinc alloys and/or composite to close a surgical wound RSS.HDBackground> Background: < Over 28 million surgeries are performed each year in America, and about 10 million operations of those are on the digestive system....

Published: 3/16/2023 | Inventor(s): Donghui Zhu

Keywords(s): Technologies

Category(s): Campus > Stony Brook University, Technology Classifications > Material and Composites, Technology Classifications > Medical Devices

Novel Fiber Membrane Distillation Process

Using hydrophobic hollow fibers to make air gap membrane distillation processes more cost-effective, efficient, and compact. Background: < Membrane distillation (MD) is a water distillation method that involves the use of hydrophobic membranes and their properties. MD allows for water vapor to permeate through a membrane but prevents...

Published: 3/16/2023 | Inventor(s): Dufei Fang, Benjamin Hsiao

Keywords(s): Technologies

Category(s): Campus > Stony Brook University, Technology Classifications > Environment, Technology Classifications > Material and Composites

Chemically Modified Curcumins (CMCs) Their Homolgues and Lower Analogues as Inhibitors of Matrix Metalloproteases (MMPs) and Pro-inflammatory Cytokkines (PICs)

Novel class of compound that display biological activities equal to or better than natural curcumin, which has been used throughout history to treat a wide variety of ailments. Background: Curcumin, a principal biological compound in the popular Indian curry spice turmeric, has been used throughout history to treat a wide variety of skin, pulmonary,...

Published: 3/16/2023 | Inventor(s): Lorne Golub

Keywords(s): Medical, Technologies

Category(s): Technology Classifications > Therapeutics

Triazamacrocycle-derived Chelators for the Coordination of Imaging and Therapy Metal Ions

Rapid and inert radiolabeling with an array of radioactive isotopes suitable for medical imaging and therapy approaches. Background: Personalized medicine, or individually tailored patient treatment, is an emerging clinical management paradigm. In nuclear medicine, this entails exploiting diagnostic techniques, such as non-invasive imaging by means...

Published: 3/16/2023 | Inventor(s): Eszter Boros, Brett Vaughn

Keywords(s): Technologies

Category(s): Campus > Stony Brook University, Technology Classifications > Medical Imaging

Novel Process for Measuring Nitrate/Nitrite and Ammonium in Wastewater Simultaneously

Using a strong alkaline solution and a gas-permeable membrane to measure the concentration of ammonium/ammonia/nitrite/nitrate in wastewater Background: Due to the growing problems with the conventional processes for treating wastewater, there has recently been a spur in the development and design of a low‑cost nitrogen sensor package that can...

Published: 3/16/2023 | Inventor(s): Qingzhi Zhu

Keywords(s): TAF, Technologies

Category(s): Campus > Stony Brook University, Technology Classifications > Environment, Technology Classifications > Research Tools and Reagents, Technology Classifications > Sensors

PI 3-Kinase Cancer Immunotherapy

Pancreatic cancer patients will be treated with a PI3K inhibitor to induce the cancer cells to reveal their antigens to the immune system Background: Standard chemotherapies have little impact on pancreatic cancer (PDAC) patient survival, and new T-cell therapies have yet to be successful in treating solid tumors. Phosphoinositide 3-kinase (PI3K),...

Published: 3/16/2023 | Inventor(s): Richard Lin

Keywords(s): cancer, immunotherapy, phosphoinositide 3-kinase (PI3K), PI3K inhibitors, Technologies

Category(s): Campus > Stony Brook University, Technology Classifications > Gene Therapy and Viral Vectors, Technology Classifications > Therapeutics

Method and Apparatus for High Efficiency X-ray Imager

An x-ray detector with improved dynamic range and sensitivity that improves the quantum efficiency of x-ray imagers Background: X-ray imaging experienced a ?digital revolution? in the early 2000s, with digital radiography systems being implemented with active matric flat panel images. Due to the compact size, rapid image readout and excellent image...

Published: 3/16/2023 | Inventor(s): Wei Zhao, Amirhossein Goldan, Adrian Howansky, Anthony Lubinsky, James Scheuermann, Jann Stavro

Keywords(s): Charge sensing, Fabrication, High Efficiency Cadmium Selenide, Multi-well, Selenium, Selenium Avalanche Multiplication Gain, Technologies, Unipolar Time-Differential (UTD)

Category(s): Campus > Stony Brook University, Technology Classifications > Nanotechnology, Technology Classifications > Optics and Photonics

Process for Predicting Community Real Estate Outcomes Using Social Media

Tracking information about communities that is not available otherwise to better predict prices Background: Technology Overview: This technology tracks information about communities that is not available otherwise. It has shown it can predict prices better than those variables alone. Advantages: Inpart-Benefits Applications: Intellectual...

Published: 3/16/2023 | Inventor(s): Hansen Schwartz, Mohammadzaman Zamani

Keywords(s): Algorithms, Data Science, Demographics, Economic Outcomes, Social Media, Technologies

Category(s): Campus > Stony Brook University, Technology Classifications > Computer Software

System and Methods for Virtual Pancreatoscopy

A virtual super-resolution pancreatoscopy method that can visualize the fine-scale structures. Background: Virtual endoscopy has been observed and claimed in many previous patents for several different organs. Among these organs is the colon, and the radiological imaging of virtual pancreatoscopy. Technology Overview: Pancreatoscopy is the endoscopic...

Published: 3/16/2023 | Inventor(s): Yi Gao, Aaron Sasson

Keywords(s): Image segmentation, pancreatic duct, Technologies, virtual endoscopy, virtual pancreatoscopy

Category(s): Campus > Stony Brook University, Technology Classifications > Computer Software, Technology Classifications > Information Technology, Technology Classifications > Medical Devices

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