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Novel EGFR Truncations as Biomarker and Target

Three mutations that could be used as biomarkers for patient's drug responses or for tumor therapeutic targets Background: Three new truncation mutants have been discovered in primary human tumors and cell lines. These mutants may possess oncogenic activities and render some tumors resistant to certain inhibitors. These newly discovered mutants...

Published: 7/21/2026 | Updated: 7/21/2026 | Inventor(s): Edward Chan, James Keller

Keywords(s): EGFR471, EGFR660, EGFR768, Technologies, truncated EGFR

Category(s): Technology Classifications > Diagnostics, Campus > Stony Brook University

Immunostimulant-Cytotoxic Conjugates for Targeted Cancer Therapy

050-9150 Immunostimulant-Cytotoxic Conjugates for Targeted Cancer Therapy A unique immunotherapy paradigm to treat castrate-resistant prostate cancer and its metastatic form RSS.HDBackground> Background: < Prostate cancer is one of the leading causes of cancer death, with 1 in 10 men diagnosed in their lifetime and 1 in 41 dying from the...

Published: 8/14/2026 | Updated: 8/9/2022 | Inventor(s): Labros Meimetis, Eszter Boros

Keywords(s): Technologies

Category(s): Technology Classifications > Drug Delivery, Campus > Stony Brook University, Technology Classifications > Drug Design and Synthesis

Bioresorbable Zinc-Based Surgical Staples

050- 9154 InPart Bioresorbable Zinc-Based Surgical Staples Biodegradable and implantable implants made of metallic zinc alloys and/or composite to close a surgical wound RSS.HDBackground> Background: < Over 28 million surgeries are performed each year in America, and about 10 million operations of those are on the digestive system....

Published: 8/14/2026 | Updated: 3/9/2022 | Inventor(s): Donghui Zhu

Keywords(s): Technologies

Category(s): Campus > Stony Brook University, Technology Classifications > Medical Devices

Triazamacrocycle-derived Chelators for the Coordination of Imaging and Therapy Metal Ions

Rapid and inert radiolabeling with an array of radioactive isotopes suitable for medical imaging and therapy approaches. Background: Personalized medicine, or individually tailored patient treatment, is an emerging clinical management paradigm. In nuclear medicine, this entails exploiting diagnostic techniques, such as non-invasive imaging by means...

Published: 2/28/2024 | Updated: 12/4/2020 | Inventor(s): Eszter Boros, Brett Vaughn

Keywords(s): Technologies

Category(s): Campus > Stony Brook University, Technology Classifications > Medical Imaging

Novel Process for Measuring Nitrate/Nitrite and Ammonium in Wastewater Simultaneously

Using a strong alkaline solution and a gas-permeable membrane to measure the concentration of ammonium/ammonia/nitrite/nitrate in wastewater Background: Due to the growing problems with the conventional processes for treating wastewater, there has recently been a spur in the development and design of a low‑cost nitrogen sensor package that can...

Published: 8/13/2026 | Updated: 10/12/2020 | Inventor(s): Qingzhi Zhu

Keywords(s): TAF, Technologies

Category(s): Campus > Stony Brook University, Technology Classifications > Environment, Technology Classifications > Research Tools and Reagents, Technology Classifications > Sensors

Method and Apparatus for High Efficiency X-ray Imager

An x-ray detector with improved dynamic range and sensitivity that improves the quantum efficiency of x-ray imagers Background: X-ray imaging experienced a ?digital revolution? in the early 2000s, with digital radiography systems being implemented with active matric flat panel images. Due to the compact size, rapid image readout and excellent image...

Published: 8/13/2026 | Updated: 8/28/2020 | Inventor(s): Wei Zhao, Amirhossein Goldan, Adrian Howansky, Anthony Lubinsky, James Scheuermann, Jann Stavro

Keywords(s): Charge sensing, Fabrication, High Efficiency Cadmium Selenide, Multi-well, Selenium, Selenium Avalanche Multiplication Gain, Technologies, Unipolar Time-Differential (UTD)

Category(s): Campus > Stony Brook University, Technology Classifications > Nanotechnology, Technology Classifications > Optics and Photonics

Process for Predicting Community Real Estate Outcomes Using Social Media

Tracking information about communities that is not available otherwise to better predict prices Background: Technology Overview: This technology tracks information about communities that is not available otherwise. It has shown it can predict prices better than those variables alone. Advantages: Inpart-Benefits Applications: Intellectual...

Published: 11/22/2023 | Updated: 8/28/2020 | Inventor(s): Hansen Schwartz, Mohammadzaman Zamani

Keywords(s): Algorithms, Data Science, Demographics, Economic Outcomes, Social Media, Technologies

Category(s): Campus > Stony Brook University, Technology Classifications > Computer Software

A Piezoelectric-triboelectric Heel Charger for Power-on-the-go

A heel charger that uses a level mechanism and a mechanical SSHI boosting circuit to provide electrical energy Background: Running out of battery power often results in life-threatening situations, whereas backup batteries are large, heavy and hazardous. In efforts to treat this unreliable aspect, proposed is an energy harvester. This is a clean...

Published: 11/22/2023 | Updated: 8/28/2020 | Inventor(s): Ya Wang, Haili Liu

Keywords(s): mechanical-synchronized (M-SSHI), piezoelectric-triboelectric materials, switch harvesting on inductor Interface (M-SSHI), Technologies

Category(s): Campus > Stony Brook University, Technology Classifications > Clean Energy, Technology Classifications > Energy Conservation

Hybrid Active Matrix Flat Panel Imager

A hybrid x-ray detector that absorbs incident rays directly and indirectly, and the photoconductor can sense both x-rays and optical photons Background: X-ray detectors currently commercially available consist of direct and indirect detectors. Direct detectors take x-ray inputs and are directly converted to electron hole pairs and digitized...

Published: 8/13/2026 | Updated: 8/28/2020 | Inventor(s): Anthony Lubinsky, Wei Zhao, Adrian Howansky, James Scheuermann

Keywords(s): direct detector, indirect detector, Selenium, Technologies, x-ray detector

Category(s): Campus > Stony Brook University, Technology Classifications > Optics and Photonics, Technology Classifications > Medical Devices

Cavity-Enhanced Two-Dimensional Spectrometer

A method to perform passively amplified 2D spectroscopy experiments with a frequency comb and optical cavities approach implemented. Background: Fundamental studies in physics and chemistry include spectroscopy of gas-phase atoms and molecules, developing essential components of quantum mechanics. Technology Overview: This invention is a...

Published: 9/9/2024 | Updated: 8/28/2020 | Inventor(s): Thomas Allison

Keywords(s): Cavity-enhanced spectroscopy, Technologies, trace gas detection., two-dimensional spectroscopy, ultrafast spectroscopy

Category(s): Campus > Stony Brook University, Technology Classifications > Optics and Photonics

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