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Modular Control of a Bioorthogonal Ligation

Caged cyclopropenes that are unreactive until activated for controlling bioorthogonal reactivity Background: Significant effort has been devoted to optimizing and discovering bioorthogonal reagents that are faster, fluorogenic, and orthogonal to the already existing bioorthogonal repertoire. Conversely, efforts to explore bioorthogonal reagents whose...

Published: 1/29/2025 | Inventor(s): Scott Laughlin, Pratik Kumar, Ting Jiang, Wei Huang

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Category(s): Campus > Stony Brook University, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays, Technology Classifications > Therapeutics