Search Results - technology+classifications+%3e+gene+therapy+and+viral+vectors

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Pancreatic cancer patients will be treated with a PI3K inhibitor to induce the cancer cells to reveal their antigens to the immune system Background: Standard chemotherapies have little impact on pancreatic cancer (PDAC) patient survival, and new T-cell therapies have yet to be successful in treating solid tumors. Phosphoinositide 3-kinase (PI3K),...

Published: 2/29/2024 | Inventor(s): Richard Lin

Keywords(s): cancer, immunotherapy, phosphoinositide 3-kinase (PI3K), PI3K inhibitors, Technologies

Category(s): Campus > Stony Brook University, Technology Classifications > Gene Therapy and Viral Vectors, Technology Classifications > Therapeutics

Novel Bioabsorbable Membranes for Cell Delivery Applications

Methods for storing viable cells and for delivering viable cells to a mammal using the cell storage and delivery system. Background: Methods and compositions for encapsulating core materials, e.g., materials containing drugs, have been disclosed. These methods generally involve encapsulating the core material within a micro capsule by forming...

Published: 11/22/2023 | Inventor(s): Benjamin Chu, Benjamin Hsiao, Michael Hadjiargyrou, Dufei Fang, Xinhua Zong, KwangSok Kim

Keywords(s):

Category(s): Campus > Stony Brook University, Technology Classifications > Drug Delivery, Technology Classifications > Drug Design and/or Synthesis, Technology Classifications > Gene Therapy and Viral Vectors

Single Chain Antibody (Mab69) Against the NG2 Proteoglycan

AAV based viral vectors that express either AAV-NG2Ab or AAV-NT3 have been shown to provide improved recovery of motor function in models. Background: Spinal Cord Injury (SCI) affects nearly 270,000 Americans and is a common cause of permanent disability and death in children and adults. Despite being a significant burden to the patients, society...

Published: 2/28/2024 | Inventor(s): Joel Levine, Victor Arvanian

Keywords(s): Technologies

Category(s): Campus > Stony Brook University, Technology Classifications > Antibodies, Technology Classifications > Gene Therapy and Viral Vectors, Technology Classifications > Therapeutics

Genetically Engineered AAV Rep for Gene Targeting and rAAV Production

Researchers at Stony Brook University have identified a genetic element within the Rep gene sequence which is inhibitory to Ad replication. Background: Gene therapy strategies have exploited lenti or retro viral approaches for long-term gene replacement, however, their clinical applications remain limited because of potential for viral-associated...

Published: 2/14/2024 | Inventor(s): Wadie Bahou, Patrick Hearing, Varsha Sitaraman

Keywords(s): Technologies

Category(s): Campus > Stony Brook University, Technology Classifications > Gene Therapy and Viral Vectors, Technology Classifications > Therapeutics, Technology Classifications > Research Tools and Reagents