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Asymmetric Charged Vesicles with Enhanced Drug Entrapment Performance
050-9175 Asymmetric Charged Vesicles with Enhanced Drug Entrapment Performance A method to improve the efficiency of liposomal drug delivery Background: Chemotherapeutic drugs and biomedicines need to be delivered effectively to their targets. This is especially true of drugs with an electric charge. In these cases, the use of the direct delivery...
Published: 8/14/2026
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Updated: 8/14/2026
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Inventor(s):
Bingchen Li
,
Erwin London
Keywords(s):
Category(s):
Technology Classifications > Drug Delivery
,
Technology Classifications > Nanotechnology
,
Campus > Stony Brook University
Metal-mediated, Autolytic Amide Bond Cleavage for the Selective, Metal-Complexation Catalyzed, Controlled Release of Metallodrugs
Autolytic, metal complex-mediated amide bond cleavage for prodrug activation and synthesis of metallodrugs RSS.HDBackground> Background: < Clinically viable prodrugs release activated drug molecules at the site of interest, requiring close spatiotemporal control. Bond cleavage strategies for the release of the activated drug often incorporate...
Published: 9/28/2026
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Updated: 1/30/2025
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Inventor(s):
Eszter Boros
,
Dariusz Śmiłowicz
Keywords(s):
Category(s):
Technology Classifications > Drug Delivery
,
Campus
,
Campus > Stony Brook University
,
Technology Classifications > Drug Design and Synthesis
Immunostimulant-Cytotoxic Conjugates for Targeted Cancer Therapy
050-9150 Immunostimulant-Cytotoxic Conjugates for Targeted Cancer Therapy A unique immunotherapy paradigm to treat castrate-resistant prostate cancer and its metastatic form RSS.HDBackground> Background: < Prostate cancer is one of the leading causes of cancer death, with 1 in 10 men diagnosed in their lifetime and 1 in 41 dying from the...
Published: 8/14/2026
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Updated: 8/9/2022
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Inventor(s):
Labros Meimetis
,
Eszter Boros
Keywords(s):
Technologies
Category(s):
Technology Classifications > Drug Delivery
,
Campus > Stony Brook University
,
Technology Classifications > Drug Design and Synthesis
Method For Treating Lateral Epicondylitis Using Collagenase
Collagenase injection for several syndromes that provides a minimally invasive and simple treatment option Background: Carpal tunnel, plantar fasciitis and lateral epicondylitis all have existing treatment methods; these methods tend to be invasive and disruptive. Carpal tunnel (a syndrome that causes tingling or numbness in the fingers) is typically...
Published: 8/27/2025
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Updated: 7/5/2020
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Inventor(s):
Marie Badalamente
,
Alexander Dagum
Keywords(s):
Technologies
Category(s):
Campus > Stony Brook University
,
Technology Classifications > Drug Delivery
,
Technology Classifications > Healthcare
Triazine-Based Tripod Linker System for Drug Delivery and Diagnosis
This tumor-targeted drug delivery system uses biotin as a tumor targeting moiety and taxoid-camptothecin combination. Background: Combination therapy is the primary treatment option against cancer, because multiple agents in combination, synergistically improve efficacy and are less prone to resistance due to their distinct action mechanisms. Despite...
Published: 7/25/2025
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Updated: 1/24/2020
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Inventor(s):
Iwao Ojima
,
Jacob Vineberg
,
Tao Wang
Keywords(s):
Technologies
Category(s):
Campus > Stony Brook University
,
Technology Classifications > Drug Delivery
,
Technology Classifications > Diagnostics
,
Technology Classifications > Drug Design and Synthesis
Asymmetric Bow-Tie Dendrimers as Versatile Platform for Drug Delivery and Diagnosis
Novel multifunctional asymmetric bow-tie dendrimers as a robust platform for drug delivery systems and diagnostic agents. Background: Dendrimers are nano-sized globular macromolecules that have been well studied as a drug delivery vehicles. Their convenient synthesis strategy, easy functionalization of the terminal end group and versatility in designing,...
Published: 7/25/2025
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Updated: 1/24/2020
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Inventor(s):
Iwao Ojima
,
Yu Han Gary Teng
,
Tao Wang
Keywords(s):
Technologies
Category(s):
Campus > Stony Brook University
,
Technology Classifications > Drug Delivery
,
Technology Classifications > Research Tools and Reagents