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Chemically Modified Curcumins (CMCs) Their Homolgues and Lower Analogues as Inhibitors of Matrix Metalloproteases (MMPs) and Pro-inflammatory Cytokkines (PICs)
Novel class of compound that display biological activities equal to or better than natural curcumin, which has been used throughout history to treat a wide variety of ailments. Background: Curcumin, a principal biological compound in the popular Indian curry spice turmeric, has been used throughout history to treat a wide variety of skin, pulmonary,...
Published: 3/16/2023
|
Inventor(s):
Lorne Golub
Keywords(s):
Medical
,
Technologies
Category(s):
Technology Classifications > Therapeutics
Methods of Treating and Preventing Angioedema and Vascular Leakage
Peptides and antibodies that block vascular permeability induced in angioedema patients that are new targets for treatment. Background: Angioedema associated with C1-INH deficiency is an inherited or acquired condition that affects 20 per cent of the population. The condition can be disfiguring, painful and sometimes fatal. Existing treatments primarily...
Published: 3/16/2023
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Inventor(s):
Berhane Ghebrehiwet
Keywords(s):
angioedema
,
gClqR
,
Medical
,
Monoclonal antibody
,
peptides
,
Technologies
,
vascular leakage
Category(s):
Campus > Stony Brook University
,
Technology Classifications > Antibodies
,
Technology Classifications > Therapeutics
Novel Bio-hybrid/Bio-functional Materials
A novel method of encapsulating microbes within crosslinked electrospun hydrogel fibers that maintain their viability. Background: Electrospinning is a process where interactions between an electrostatic field and a fluid are utilized to form nanoscale and microscale polymer fibers. These fibers can be collected to form an interconnected web of fibers,...
Published: 3/16/2023
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Inventor(s):
Ying Liu
,
Miriam Rafailovich
Keywords(s):
Medical
Category(s):
Campus > Stony Brook University
,
Technology Classifications > Material and Composites