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Novel 18F-Labeled PET-Tracers for Use in Treatment of Neurological Disorders

Novel 18F-labeled GSK3β inhibitors that can cross the blood brain barrier. Background: Dysregulation of Glycogen Synthase Kinase 3β (GSK3β) is associated with several neurodegenerative diseases, such as Parkinson’s, Alzheimer’s and Huntington’s. Therefore, development of a selective GSK3β PET tracer would enable...

Published: 3/16/2023 | Inventor(s): Ming-Yu Ngai, Katarzyna Lee, Kongzhen Hu, Neil Nasdev, Stephen Haggarty

Keywords(s): Technologies

Category(s): Campus > Stony Brook University, Technology Classifications > Drug Design and/or Synthesis, Technology Classifications > Diagnostics, Technology Classifications > Therapeutics