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Concerted, Selective Radiometallation and Photo-triggered Release of Ready-to-Inject Radiopharmaceuticals from the Solid Phase
Solid Phase Radiometallation Photorelease method for the preparation of injectable radiopharmaceuticals RSS.HDBackground> Background: < Radiopharmaceuticals are agents which enable non-invasive patient diagnosis and personalized therapeutic intervention strategies. Radionuclides used in nuclear medicine applications must be purified after nuclear...
Published: 2/4/2025
|
Inventor(s):
Eszter Boros
,
Dariusz Śmiłowicz
Keywords(s):
Category(s):
Technology Classifications > Diagnostics
,
Technology Classifications > Drug Design and/or Synthesis
,
Campus > Stony Brook University
Metal-mediated, Autolytic Amide Bond Cleavage for the Selective, Metal-Complexation Catalyzed, Controlled Release of Metallodrugs
Autolytic, metal complex-mediated amide bond cleavage for prodrug activation and synthesis of metallodrugs RSS.HDBackground> Background: < Clinically viable prodrugs release activated drug molecules at the site of interest, requiring close spatiotemporal control. Bond cleavage strategies for the release of the activated drug often incorporate...
Published: 2/4/2025
|
Inventor(s):
Eszter Boros
,
Dariusz Śmiłowicz
Keywords(s):
Category(s):
Technology Classifications > Drug Design and/or Synthesis
,
Technology Classifications > Drug Delivery
,
Campus
,
Campus > Stony Brook University