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Genetically Engineered AAV Rep for Gene Targeting and rAAV Production

Researchers at Stony Brook University have identified a genetic element within the Rep gene sequence which is inhibitory to Ad replication. Background: Gene therapy strategies have exploited lenti or retro viral approaches for long-term gene replacement, however, their clinical applications remain limited because of potential for viral-associated...

Published: 2/14/2024 | Inventor(s): Wadie Bahou, Patrick Hearing, Varsha Sitaraman

Keywords(s): Technologies

Category(s): Campus > Stony Brook University, Technology Classifications > Gene Therapy and Viral Vectors, Technology Classifications > Therapeutics, Technology Classifications > Research Tools and Reagents