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Novel EGFR Truncations as Biomarker and Target

Three mutations that could be used as biomarkers for patient's drug responses or for tumor therapeutic targets Background: Three new truncation mutants have been discovered in primary human tumors and cell lines. These mutants may possess oncogenic activities and render some tumors resistant to certain inhibitors. These newly discovered mutants...

Published: 10/2/2024 | Inventor(s): Edward Chan, James Keller

Keywords(s): EGFR471, EGFR660, EGFR768, Technologies, truncated EGFR

Category(s): Campus > Stony Brook University, Technology Classifications > Diagnostics