Search Results - drug+delivery

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Novel Prodrugs for Selective Anticancer Therapy
Novel methods to make anticancer prodrugs by conjugating unique dual-substrate biochemical modules to known or novel chemotherapeutic drugs Background: Anticancer drug sales exceeded $50 billion worldwide in 2009 with impressive growth; however, lack of target selectivity is a major challenge in cancer treatment. The limitation of current chemotherapy...
Published: 8/27/2020   |   Inventor(s): Michael Hayman, Nobuhide Ueki
Keywords(s): anticancer drugs, cancer-associated protease, HDAC, nucleoside analogues, Technologies
Category(s): Therapeutics, Drug Delivery, Drug Design and/or Synthesis, Campus > Stony Brook University
Porous Graphene Based Composite Membranes for Nanofiltration, Desalination and Pervaporation
An ultra-thin barrier from a single atomic layer of graphene-based materials with adjustable pore size Background: For membrane separation technology, preparing a very thin barrier layer with high selectivity, high throughput, low fouling, and long lasting properties forms the ultimate set of goals, which the widely used polymeric materials...
Published: 8/25/2020   |   Inventor(s): Benjamin Chu, Benjamin Hsiao, Hongyang Ma, Zhe Wang
Keywords(s): chemically cross-linking, desalination, electrospun scaffold, membrane, nanofiltration, pervaporation, Porous graphene oxide, Technologies, water channels
Category(s): Drug Delivery, Education and Training, Medical Devices, Campus > Stony Brook University
Degradable Polymeric Materials via Large Ring Alternating Ring Opening Metathesis Polymerization (AROMP)
An effective way of designing a myriad of intelligent materials that are readily degradable and easily synthesized Background: Ring opening metathesis polymerization is a technique which enables the synthesis of materials of diverse architecture owing to its tolerance to a large range of functionalities. Traditionally, the scope of monomers used yields...
Published: 7/6/2020   |   Inventor(s): Nicole Sampson, Jingling Zhang, Francis Boadi, Guofang Li
Category(s): Drug Delivery, Electronics and Electronic Materials, Material and Composites, Therapeutics, Campus > Stony Brook University
Novel Bioabsorbable Membranes for Cell Delivery Applications
Methods for storing viable cells and for delivering viable cells to a mammal using the cell storage and delivery system. Background: Methods and compositions for encapsulating core materials, e.g., materials containing drugs, have been disclosed. These methods generally involve encapsulating the core material within a micro capsule by forming...
Published: 7/5/2020   |   Inventor(s): Benjamin Chu, Benjamin Hsiao, Michael Hadjiargyrou, Dufei Fang, Xinhua Zong, Kwangsok Kim
Category(s): Drug Delivery, Drug Design and/or Synthesis, Campus > Stony Brook University, Gene Therapy and Viral Vectors
Triazibe-Based Tripod Linker System for Drug Delivery and Diagnosis
This tumor-targeted drug delivery system uses biotin as a tumor targeting moiety and taxoid-camptothecin combination. Background: Combination therapy is the primary treatment option against cancer, because multiple agents in combination, synergistically improve efficacy and are less prone to resistance due to their distinct action mechanisms. Despite...
Published: 1/24/2020   |   Inventor(s): Iwao Ojima, Jacob Vineberg, Tao Wang
Keywords(s): Technologies
Category(s): Drug Delivery, Diagnostics, Drug Design and/or Synthesis, Therapeutics, Campus > Stony Brook University
Asymmetric Bow-Tie Dendrimers as Versatile Platform for Drug Delivery and Diagnosis
Novel multifunctional asymmetric bow-tie dendrimers as a robust platform for drug delivery systems and diagnostic agents. Background: Dendrimers are nano-sized globular macromolecules that have been well studied as a drug delivery vehicles. Their convenient synthesis strategy, easy functionalization of the terminal end group and versatility in designing,...
Published: 1/24/2020   |   Inventor(s): Iwao Ojima, Yu Han Gary Teng, Tao Wang
Keywords(s): Technologies
Category(s): Drug Delivery, Therapeutics, Research Tools and Reagents, Campus > Stony Brook University